Literature summary for 3.4.23.39 extracted from

Valiente, P.A.; Batista, P.R.; Pupo, A.; Pons, T.; Valencia, A.; Pascutti, P.G.
Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations (2008), Proteins, 73, 440-457.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
sequence and structural analysis combined with molecular dynamics simulations to predict the functional residues. Residues Y17, V105, T108, L191, L242, Q275, and T298 are important for plasmepsin function. Residues V105 and T108 are localized in a flap of an interior pocket. There is a rapid conformational change in the L3 region of plasmepsins that closes the active site	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	P46925	-	-

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Release 2023.1 (January 2023)