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Literature summary for 3.4.23.39 extracted from

  • Westling, J.; Cipullo, P.; Hung, S.H.; Saft, H.; Dame, J.B.; Dunn, B.M.
    Active site specificity of plasmepsin II (1999), Protein Sci., 8, 2001-2009.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.23.39

Protein Variants

Protein Variants Comment Organism
I287E changes in substrate specificity compared to wild-type enzyme, the turnover-number for Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro is 42% of that of the wild-type enzyme, the Km-value is 51% of that of the wild-type enzyme Plasmodium falciparum
M13E the turnover-number for Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro is 1.16fold higher than the turnover-number of the wild-type enzyme, the Km-value is 54% of that of the wild-type enzyme Plasmodium falciparum
M13E/I287E changes in substrate specificity compared to wild-type enzyme, the turnover-number for Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro is 1.48fold higher than the turnover-number of the wild-type enzyme, the Km-value is 1.23fold higher than that of the wild-type enzyme Plasmodium falciparum
S77D changes in substrate specificity compared to wild-type enzyme, cleavage of Lys-Glu-Phe-Val-Lys-Phe(NO2)-Ala-Leu-Lys that is not cleaved by the wild-type enzyme, the turnover-number for Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-is 54% of the turnover-number of the wild-type enzyme, the Km-value is 71% of that of the wild-type enzyme Plasmodium falciparum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
 Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.006
-
 Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.008
-
 Lys-Pro-Ile-Leu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.013
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Ala-Leu pH 4.4, 37°C Plasmodium falciparum
0.013
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Ile pH 4.4, 37°C Plasmodium falciparum
0.0139
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.0146
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.016
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Val-Leu pH 4.4, 37°C Plasmodium falciparum
0.017
-
 Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.017
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Val pH 4.4, 37°C Plasmodium falciparum
0.0192
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
0.021
-
 Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.022
-
 Lys-Pro-Ile-Nle-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.023
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.024
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.024
-
 Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.03
-
 Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.031
-
 Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.0334
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.035
-
 Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.036
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.037
-
 Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.037
-
 Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.037
-
 Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.039
-
 Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.04
-
 Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
0.041
-
 Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.045
-
 Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.046
-
 Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.046
-
 Lys-Glu-Phe-Val-Lys-Phe(NO2)-Ala-Leu-Lys pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
0.049
-
 Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.05
-
 Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.051
-
 Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.052
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Ser-Leu pH 4.4, 37°C Plasmodium falciparum
0.052
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
0.053
-
 Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.055
-
 Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.055
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.056
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Lys-Leu pH 4.4, 37°C Plasmodium falciparum
0.056
-
 Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.058
-
 Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.064
-
 Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.067
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Ser pH 4.4, 37°C Plasmodium falciparum
0.069
-
 Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.07
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.07
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.07
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.07
-
 Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.071
-
 Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.073
-
 Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.075
-
 Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.076
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.081
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Glu-Leu pH 4.4, 37°C Plasmodium falciparum
0.085
-
 Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.087
-
 Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.088
-
 Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.092
-
 Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.1
-
 Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.101
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Asp pH 4.4, 37°C Plasmodium falciparum
0.109
-
 Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.11
-
 Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.117
-
 Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.171
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Arg pH 4.4, 37°C Plasmodium falciparum
0.221
-
 Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.25
-
 Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro + H2O
-
 Plasmodium falciparum Ala-Leu-Glu-Arg-Nle-Phe + Phe(NO2)-Ser-Phe-Pro
-
 ?
Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Ala-Ile-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Asp-Ile-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Glu-Phe-Val-Lys-Phe(NO2)-Ala-Leu-Lys + H2O
-
 Plasmodium falciparum Lys-Glu-Phe-Val-Lys + Phe(NO2)-Ala-Leu-Lys +
-
 ?
Lys-Glu-Phe-Val-Lys-Phe(NO2)-Ala-Leu-Lys + H2O
-
 Plasmodium falciparum ?
-
 ?
Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Lys-Ile-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Phe-Ile-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ala-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Asp-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Ala-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Asp-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Ala-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Ala-Leu
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Arg + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Arg-Arg
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Asp + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Arg-Asp
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Ile + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Arg-Ile
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Ser + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Arg-Ser
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Val + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Arg-Val
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Glu-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Glu-Leu
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Lys-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Lys-Leu
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Ser-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Ser-Leu
-
 ?
Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Val-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Glu-Phe + Phe(NO2)-Val-Leu
-
 ?
Lys-Pro-Ile-Leu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Leu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Lys-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Nle-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Nle-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ile-Ser-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Lys-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Phe-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Pro-Ser-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?
Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu + H2O
-
 Plasmodium falciparum Lys-Ser-Ile-Glu-Phe + Phe(NO2)-Arg-Leu
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.03
-
 Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.05
-
 Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.06
-
 Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.08
-
 Lys-Pro-Ile-Lys-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
0.08
-
 Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.1
-
 Lys-Pro-Lys-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.17
-
 Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.19
-
 Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.2
-
 Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.25
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.27
-
 Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.3
-
 Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.32
-
 Lys-Pro-Ser-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.32
-
 Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.4
-
 Lys-Pro-Asp-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.4
-
 Lys-Lys-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.44
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Ser pH 4.4, 37°C Plasmodium falciparum
0.44
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.5
-
 Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.5
-
 Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.53
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Arg pH 4.4, 37°C Plasmodium falciparum
0.53
-
 Lys-Pro-Ala-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
0.6
-
 Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.7
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Val pH 4.4, 37°C Plasmodium falciparum
0.73
-
 Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
0.73
-
 Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.8
-
 Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.84
-
 Lys-Glu-Phe-Val-Lys-Phe(NO2)-Ala-Leu-Lys pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
0.86
-
 Lys-Pro-Ile-Asp-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.89
-
 Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
0.9
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Ile pH 4.4, 37°C Plasmodium falciparum
0.9
-
 Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.9
-
 Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
0.91
-
 Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
1
-
 Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
1
-
 Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
1.1
-
 Lys-Asp-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
1.1
-
 Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
1.1
-
 Lys-Pro-Ile-Ser-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
1.1
-
 Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
1.2
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Asp pH 4.4, 37°C Plasmodium falciparum
1.3
-
 Lys-Ser-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
1.6
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Lys-Leu pH 4.4, 37°C Plasmodium falciparum
1.7
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Ser-Leu pH 4.4, 37°C Plasmodium falciparum
1.7
-
 Lys-Pro-Ile-Leu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
1.7
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
1.8
-
 Lys-Pro-Ile-Ala-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
2
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
2
-
 Lys-Ala-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
2
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
2
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
2.1
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme I287E Plasmodium falciparum
2.4
-
 Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
2.6
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Val-Leu pH 4.4, 37°C Plasmodium falciparum
2.6
-
 Lys-Phe-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
2.7
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme S77D Plasmodium falciparum
2.9
-
 Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
3.1
-
 Lys-Pro-Ile-Nle-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C Plasmodium falciparum
3.1
-
 Lys-Pro-Phe-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
3.5
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Arg-Leu pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum
5.7
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Ala-Leu pH 4.4, 37°C Plasmodium falciparum
5.8
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme M13E Plasmodium falciparum
6.3
-
 Lys-Pro-Ile-Glu-Phe-Phe(NO2)-Glu-Leu pH 4.4, 37°C Plasmodium falciparum
7.4
-
 Ala-Leu-Glu-Arg-Nle-Phe-Phe(NO2)-Ser-Phe-Pro pH 4.4, 37°C, mutant enzyme M13E/I287E Plasmodium falciparum