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Literature summary for 3.4.23.35 extracted from

  • MacKay, V.L.; Welch, S.K.; Insley, M.Y.; Manney, T.R.; Holly, J.; Saari, G.C.; Parker, M.L.
    The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin (1988), Proc. Natl. Acad. Sci. USA, 85, 55-59.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.23.35

Cloned(Commentary)

Cloned (Comment) Organism
Saccharomyces cerevisiae, by in vivo complementation of a bar1 mutation in yeast strain XP635-10C Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
additional information no inhibition by EDTA, 6-aminohexanoic acid, PMSF, aprotinin, leupeptin, tosyl-Lys methyl ester, pepstatin A Saccharomyces cerevisiae
tosyl-Arg methyl ester not Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Saccharomyces cerevisiae
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha Factor + H2O Saccharomyces cerevisiae i.e. Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, involved in physiological changes preceding Saccharomyces cerevisiae cell fusion ?
-
 ?
alpha Factor + H2O Saccharomyces cerevisiae acts as antagonist of alpha factor, the peptide mating pheromone produced by mating type alpha-cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 baker's yeast mutant strains
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha Factor + H2O cleavage site: Leu6-Lys7 Saccharomyces cerevisiae Trp-His-Trp-Leu-Gln-Leu + Lys-Pro-Gly-Gln-Pro-Met-Tyr
-
 ?
alpha Factor + H2O i.e. Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, a Saccharomyces cerevisiae peptide mating pheromone secreted by mating-type alpha cells Saccharomyces cerevisiae Trp-His-Trp-Leu-Gln-Leu + Lys-Pro-Gly-Gln-Pro-Met-Tyr
-
 ?
alpha Factor + H2O i.e. Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, involved in physiological changes preceding Saccharomyces cerevisiae cell fusion Saccharomyces cerevisiae ?
-
 ?
alpha Factor + H2O acts as antagonist of alpha factor, the peptide mating pheromone produced by mating type alpha-cells Saccharomyces cerevisiae ?
-
 ?