Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
MOCAc-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2 + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
MOCAc-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2 + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CatE | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | MOG35-55 directly binds to toll-like receptor 4, which leads to increased production of the enzyme in neutrophils | down |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme-deficient mice are highly resistant to myelin oligodendrocyte glycoprotein 35-55-induced mechanical allodynia | Mus musculus |
physiological function | cathepsin E in neutrophils contributes to the generation of mechanical allodynia in experimental autoimmune encephalomyelitis. The enzyme is required for the enzymatic activity of elastase in neutrophils after myelin oligodendrocyte glycoprotein 35-55 stimulation | Mus musculus |