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Literature summary for 3.4.23.34 extracted from

  • Kawakubo, T.; Okamoto, K.; Iwata, J.; Shin, M.; Okamoto, Y.; Yasukochi, A.; Nakayama, K.I.; Kadowaki, T.; Tsukuba, T.; Yamamoto, K.
    Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface (2007), Cancer Res., 67, 10869-10878.
    View publication on PubMed

Application

Application Comment Organism
medicine antitumor activity of cathepsin E in human prostate carcinoma tumor cell lines Mus musculus
molecular biology CatE is a potential cancer biomarker Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK293T cells of wild-type and mutant form Mus musculus

Protein Variants

Protein Variants Comment Organism
D98A/D283A expression in HEK293T cells Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Purification (Commentary)

Purification (Comment) Organism
DEAE-Sephacel chromatography and immunodepletion Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
phagocyte cathepsin E is secreted by activated phagocytes Mus musculus
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