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Literature summary for 3.4.23.34 extracted from
- Cathepsin E: a mini review (2008), Biochem. Biophys. Res. Commun., 367, 517-522.
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | CatE is essential for processing of ovalbumin by murine B-cells, Cat E could play a major role in antigen processing, involvement of CatE in the MHC class II pathway | Mus musculus |
| additional information | CatE is essential for processing of ovalbumin by murine B-cells, Cat E could play a major role in antigen processing, involvement of CatE in the MHC class II pathway | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ascaris pepsin inhibitor | - |
Homo sapiens | |
| Ascaris pepsin inhibitor | - |
Mus musculus | |
| PepA-penetratin | efficient cell-permeable aspartic protease inhibitor | Homo sapiens | |
| PepA-penetratin | efficient cell-permeable aspartic protease inhibitor | Mus musculus | |
| pepstatin A | pepA | Homo sapiens |  |
| pepstatin A | pepA | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | in different cell types such as gastric epithelial cells, Langerhans cells, interdigitating reticulum cell and human M cells | Mus musculus | 5783 | - |
| endoplasmic reticulum | in different cell types such as gastric epithelial cells, Langerhans cells, interdigitating reticulum cell and human M cells | Homo sapiens | 5783 | - |
| endosome | in antigen-presenting cells such as microglia, dendritic cells and macrophagess CatE is mainly present in the endosomal compartments | Mus musculus | 5768 | - |
| endosome | in antigen-presenting cells such as microglia, dendritic cells and macrophagess CatE is mainly present in the endosomal compartments | Homo sapiens | 5768 | - |
| Golgi complex | in different cell types such as gastric epithelial cells, Langerhans cells, interdigitating reticulum cell and human M cells | Mus musculus | - |
- |
| Golgi complex | in different cell types such as gastric epithelial cells, Langerhans cells, interdigitating reticulum cell and human M cells | Homo sapiens | - |
- |
| lysosome | Cat E is partially present in lysosomes | Mus musculus | 5764 | - |
| lysosome | Cat E is partially present in lysosomes | Homo sapiens | 5764 | - |
| plasma membrane | in erythrocytes, gastric cells, renal proximal tubule cells and osteoclasts | Mus musculus | 5886 | - |
| plasma membrane | in erythrocytes, gastric cells, renal proximal tubule cells and osteoclasts | Homo sapiens | 5886 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture condition:antigen-presenting cell | APC | Mus musculus | - |
| culture condition:antigen-presenting cell | APC | Homo sapiens | - |
| dendritic cell | - |
Mus musculus | - |
| dendritic cell | - |
Homo sapiens | - |
| erythrocyte | human and rat | Mus musculus | - |
| erythrocyte | human and rat | Homo sapiens | - |
| gastric epithelial cell | - |
Mus musculus | - |
| gastric epithelial cell | - |
Homo sapiens | - |
| glial cell | of aged rat | Mus musculus | - |
| interdigitating reticulum cell | - |
Mus musculus | - |
| interdigitating reticulum cell | - |
Homo sapiens | - |
| Langerhans cell | - |
Mus musculus | - |
| Langerhans cell | - |
Homo sapiens | - |
| lymphocyte | but not in resting B-lymphocytes | Mus musculus | - |
| lymphocyte | but not in resting B-lymphocytes | Homo sapiens | - |
| M cell | human M cell | Homo sapiens | - |
| microglia | - |
Mus musculus | - |
| microglia | - |
Homo sapiens | - |
| neuron | of aged rat | Mus musculus | - |
| osteoclast | - |
Mus musculus | - |
| osteoclast | - |
Homo sapiens | - |
| pancreatic ductal carcinoma cell | - |
Mus musculus | - |
| pancreatic ductal carcinoma cell | - |
Homo sapiens | - |
| pancreatic juice | - |
Mus musculus | - |
| pancreatic juice | - |
Homo sapiens | - |
| red blood cell | of human and rat but not in guinea pig, cattle, goat or pig | Mus musculus | - |
| red blood cell | of human and rat but not in guinea pig, cattle, goat or pig | Homo sapiens | - |
| renal proximal tubule | - |
Mus musculus | - |
| renal proximal tubule | - |
Homo sapiens | - |
| spleen | rat | Mus musculus | - |
| stomach | rat | Mus musculus | - |
| thymocyte | rat | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(dinitrophenyl)-D-Arg-NH2 | - |
Mus musculus | (7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Leu-Phe + Phe-Arg-Leu-Lys(dinitrophenyl)-D-Arg-NH2 | - |
? | |
| (7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(dinitrophenyl)-D-Arg-NH2 | - |
Homo sapiens | (7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Leu-Phe + Phe-Arg-Leu-Lys(dinitrophenyl)-D-Arg-NH2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CatE | - |
Mus musculus |
| CatE | - |
Homo sapiens |
| cathepsin D-like protease | - |
Mus musculus |
| cathepsin D-like protease | - |
Homo sapiens |
| erythrocyte membrane acid proteinase | - |
Mus musculus |
| erythrocyte membrane acid proteinase | - |
Homo sapiens |
| gastric mucosa non-pepsin acid proteinase | - |
Mus musculus |
| gastric mucosa non-pepsin acid proteinase | - |
Homo sapiens |
| slow moving proteinase | - |
Mus musculus |
| slow moving proteinase | - |
Homo sapiens |
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