Literature summary for 3.4.23.3 extracted from

Reid, W.A.; Vongsorasak, L.; Svasti, J.; Valler, M.J.; Kay, J.
Identification of the acid proteinase in human seminal fluid as a gastricsin originating in the prostate (1984), Cell Tissue Res., 236, 597-600.

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Inhibitors

Inhibitors	Comment	Organism	Structure
isovaleryl pepstatin	-	Homo sapiens
lactoyl-pepstatin	very weakly	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.42	-	Pro-Thr-Glu-Phe-(NO2)Phe-Arg-Leu	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	progastricsin, MW 34000 Da is converted by acid activation to gastricsin, 31000 Da	Homo sapiens
proteolytic modification	zymogen: progastricsin	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
semen	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Pro-Thr-Glu-Phe-(NO2)Phe-Arg-Leu + H2O	-	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)