Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
[Candida] glabrata | 9986 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
[Candida] glabrata | - |
- |
- |
[Candida] glabrata BG2 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
aspartyl protease | - |
[Candida] glabrata |
yapsin | - |
[Candida] glabrata |
Yps | - |
[Candida] glabrata |
General Information | Comment | Organism |
---|---|---|
malfunction | the Cgyps1-11 mutant lacking all 11 enzyme genes displays pleiotropic defects, including increased susceptibility to cell wall and osmotic stress, perturbed vacuole and pH homeostasis, and attenuated intracellular survival and pathogenesis | [Candida] glabrata |
physiological function | the enzyme is required for suppression of the host innate immune response by suppressing the interleukin-1production in macrophages. The enzyme genes are required for organ colonization and dissemination in a mouse model of systemic infection | [Candida] glabrata |