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Literature summary for 3.4.23.23 extracted from

  • Sternberg, M.
    Bond specificity, active site and milk clotting mechanism of the Mucor miehei protease (1972), Biochim. Biophys. Acta, 285, 383-392.
    View publication on PubMed
Search for more literature for 3.4.23.23

Inhibitors

Inhibitors Comment Organism Structure
2,4-Dinitro-1-fluorobenzene
-
 Rhizomucor miehei
Diazoacetyl-glycyl ethyl ester in presence of copper ions Rhizomucor miehei

Organism

Organism UniProt Comment Textmining
Rhizomucor miehei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Benzyloxycarbonyl-Gly-Phe-Phe + H2O
-
 Rhizomucor miehei ?
-
 ?
Benzyloxycarbonyl-Phe-Tyr + H2O
-
 Rhizomucor miehei ?
-
 ?
additional information milk clotting activity Rhizomucor miehei ?
-
 ?
additional information specificity against aromatic bulky or hydrophobic amino acid residues at both sides of the splitting point Rhizomucor miehei ?
-
 ?
Oxidized insulin B-chain + H2O hydrolysis at: Phe1-Val2, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Phe24-Phe25, Phe25-Tyr26, Tyr26-Thr27 Rhizomucor miehei Hydrolyzed oxidized B-chain of insulin
-
 ?
Peptides + H2O carbobenzoxy-Phe-Met methyl ester containing the bond involved in milk clotting mechanism is not hydrolyzed unless it becomes part of a polypeptide with tails of carbobenzoxy-Phe-Met anchored on a polylysine chain Rhizomucor miehei Hydrolyzed peptides
-
 ?
Proteins + H2O preferentially hydrolyzes peptide bonds having an aromatic amino acid as carboxyl donor Rhizomucor miehei Hydrolyzed proteins
-
 ?
Proteins + H2O involving aromatic residues Rhizomucor miehei Hydrolyzed proteins
-
 ?
Val-Tyr-Val + H2O
-
 Rhizomucor miehei ?
-
 ?