BRENDA - Enzyme Database
show all sequences of 3.4.23.23

Aspartic proteinases from Mucor spp. in cheese manufacturing

Yegin, S.; Fernandez-Lahore, M.; Jose Gama Salgado, A.; Guvenc, U.; Goksungur, Y.; Tari, C.; Appl. Microbiol. Biotechnol. 89, 949-960 (2011)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
pepstatin A
-
Amylomyces rouxii
pepstatin A
-
Aspergillus oryzae
pepstatin A
-
Cryphonectria parasitica
pepstatin A
-
Mucor bacilliformis
pepstatin A
-
Mucor circinelloides
pepstatin A
-
Mucor hiemalis
pepstatin A
-
Mucor racemosus f. racemosus
pepstatin A
-
Mucor renninus
pepstatin A
-
Penicillium duponti
pepstatin A
-
Rhizomucor miehei
pepstatin A
-
Rhizomucor pusillus
pepstatin A
-
Rhizopus oryzae
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
16000
-
x * 16000
Amylomyces rouxii
33000
-
x * 33000
Mucor circinelloides
34000
-
x * 34000
Rhizopus oryzae
35000
-
x * 35000
Mucor renninus
38500
-
x * 38500, SDS-PAGE
Rhizomucor pusillus
41000
-
x * 41000
Penicillium duponti
47000
-
x * 47000
Aspergillus oryzae
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Amylomyces rouxii
-
-
-
Aspergillus oryzae
-
-
-
Cryphonectria parasitica
-
-
-
Mucor bacilliformis
-
-
-
Mucor circinelloides
-
-
-
Mucor hiemalis
-
-
-
Mucor racemosus f. racemosus
-
-
-
Mucor renninus
-
-
-
Penicillium duponti
-
-
-
Rhizomucor miehei
-
-
-
Rhizomucor pusillus
-
-
-
Rhizopus oryzae
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
casein + H2O
low enzyme activity
717133
Rhizopus oryzae
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Penicillium duponti
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Aspergillus oryzae
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Cryphonectria parasitica
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Rhizomucor miehei
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Rhizomucor pusillus
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor bacilliformis
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor renninus
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Amylomyces rouxii
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor hiemalis
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor circinelloides
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor racemosus f. racemosus
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Rhizopus oryzae
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Penicillium duponti
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Aspergillus oryzae
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Cryphonectria parasitica
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Rhizomucor miehei
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Rhizomucor pusillus
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor bacilliformis
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor renninus
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Amylomyces rouxii
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor hiemalis
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor circinelloides
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor racemosus f. racemosus
?
-
-
-
?
soybean meal + H2O
-
717133
Rhizopus oryzae
?
-
-
-
?
soybean meal + H2O
-
717133
Penicillium duponti
?
-
-
-
?
soybean meal + H2O
-
717133
Aspergillus oryzae
?
-
-
-
?
soybean meal + H2O
-
717133
Cryphonectria parasitica
?
-
-
-
?
soybean meal + H2O
-
717133
Rhizomucor miehei
?
-
-
-
?
soybean meal + H2O
-
717133
Rhizomucor pusillus
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor bacilliformis
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor renninus
?
-
-
-
?
soybean meal + H2O
-
717133
Amylomyces rouxii
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor hiemalis
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor circinelloides
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor racemosus f. racemosus
?
-
-
-
?
wheat bran + H2O
-
717133
Rhizopus oryzae
?
-
-
-
?
wheat bran + H2O
-
717133
Penicillium duponti
?
-
-
-
?
wheat bran + H2O
-
717133
Aspergillus oryzae
?
-
-
-
?
wheat bran + H2O
-
717133
Cryphonectria parasitica
?
-
-
-
?
wheat bran + H2O
-
717133
Rhizomucor miehei
?
-
-
-
?
wheat bran + H2O
-
717133
Rhizomucor pusillus
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor bacilliformis
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor renninus
?
-
-
-
?
wheat bran + H2O
-
717133
Amylomyces rouxii
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor hiemalis
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor circinelloides
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor racemosus f. racemosus
?
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 16000
Amylomyces rouxii
?
x * 47000
Aspergillus oryzae
?
x * 34000-39000
Cryphonectria parasitica
?
x * 32000-35000
Mucor bacilliformis
?
x * 33000
Mucor circinelloides
?
x * 35000
Mucor renninus
?
x * 41000
Penicillium duponti
?
x * 20000-43000
Rhizomucor miehei
?
x * 38500, SDS-PAGE
Rhizomucor pusillus
?
x * 34000
Rhizopus oryzae
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
45
-
-
Mucor bacilliformis
50
-
-
Amylomyces rouxii
55
-
-
Aspergillus oryzae
55
-
-
Penicillium duponti
55
-
-
Rhizomucor pusillus
58
62
-
Rhizomucor miehei
60
-
-
Rhizopus oryzae
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.5
-
-
Penicillium duponti
3
3.5
-
Mucor bacilliformis
3
3.5
-
Mucor circinelloides
3
3.5
-
Mucor hiemalis
3
-
-
Mucor racemosus f. racemosus
3.2
-
-
Aspergillus oryzae
3.5
-
-
Mucor renninus
4
-
-
Amylomyces rouxii
4.5
-
-
Cryphonectria parasitica
5.5
-
-
Rhizopus oryzae
5.6
-
-
Rhizomucor miehei
5.6
-
-
Rhizomucor pusillus
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Penicillium duponti
isoelectric focusing
-
3.9
Rhizomucor pusillus
isoelectric focusing
-
3.9
Rhizomucor miehei
isoelectric focusing
-
4.1
Mucor circinelloides
isoelectric focusing
-
4.2
Mucor renninus
isoelectric focusing
-
5.1
Mucor bacilliformis
isoelectric focusing
-
5.2
Cryphonectria parasitica
isoelectric focusing
-
5.5
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
pepstatin A
-
Amylomyces rouxii
pepstatin A
-
Aspergillus oryzae
pepstatin A
-
Cryphonectria parasitica
pepstatin A
-
Mucor bacilliformis
pepstatin A
-
Mucor circinelloides
pepstatin A
-
Mucor hiemalis
pepstatin A
-
Mucor racemosus f. racemosus
pepstatin A
-
Mucor renninus
pepstatin A
-
Penicillium duponti
pepstatin A
-
Rhizomucor miehei
pepstatin A
-
Rhizomucor pusillus
pepstatin A
-
Rhizopus oryzae
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
16000
-
x * 16000
Amylomyces rouxii
33000
-
x * 33000
Mucor circinelloides
34000
-
x * 34000
Rhizopus oryzae
35000
-
x * 35000
Mucor renninus
38500
-
x * 38500, SDS-PAGE
Rhizomucor pusillus
41000
-
x * 41000
Penicillium duponti
47000
-
x * 47000
Aspergillus oryzae
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
casein + H2O
low enzyme activity
717133
Rhizopus oryzae
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Penicillium duponti
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Aspergillus oryzae
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Cryphonectria parasitica
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Rhizomucor miehei
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Rhizomucor pusillus
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor bacilliformis
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor renninus
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Amylomyces rouxii
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor hiemalis
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor circinelloides
?
-
-
-
?
casein + H2O
low enzyme activity
717133
Mucor racemosus f. racemosus
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Rhizopus oryzae
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Penicillium duponti
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Aspergillus oryzae
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Cryphonectria parasitica
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Rhizomucor miehei
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Rhizomucor pusillus
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor bacilliformis
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor renninus
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Amylomyces rouxii
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor hiemalis
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor circinelloides
?
-
-
-
?
Gelatin + H2O
low enzyme activity
717133
Mucor racemosus f. racemosus
?
-
-
-
?
soybean meal + H2O
-
717133
Rhizopus oryzae
?
-
-
-
?
soybean meal + H2O
-
717133
Penicillium duponti
?
-
-
-
?
soybean meal + H2O
-
717133
Aspergillus oryzae
?
-
-
-
?
soybean meal + H2O
-
717133
Cryphonectria parasitica
?
-
-
-
?
soybean meal + H2O
-
717133
Rhizomucor miehei
?
-
-
-
?
soybean meal + H2O
-
717133
Rhizomucor pusillus
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor bacilliformis
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor renninus
?
-
-
-
?
soybean meal + H2O
-
717133
Amylomyces rouxii
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor hiemalis
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor circinelloides
?
-
-
-
?
soybean meal + H2O
-
717133
Mucor racemosus f. racemosus
?
-
-
-
?
wheat bran + H2O
-
717133
Rhizopus oryzae
?
-
-
-
?
wheat bran + H2O
-
717133
Penicillium duponti
?
-
-
-
?
wheat bran + H2O
-
717133
Aspergillus oryzae
?
-
-
-
?
wheat bran + H2O
-
717133
Cryphonectria parasitica
?
-
-
-
?
wheat bran + H2O
-
717133
Rhizomucor miehei
?
-
-
-
?
wheat bran + H2O
-
717133
Rhizomucor pusillus
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor bacilliformis
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor renninus
?
-
-
-
?
wheat bran + H2O
-
717133
Amylomyces rouxii
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor hiemalis
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor circinelloides
?
-
-
-
?
wheat bran + H2O
-
717133
Mucor racemosus f. racemosus
?
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 16000
Amylomyces rouxii
?
x * 47000
Aspergillus oryzae
?
x * 34000-39000
Cryphonectria parasitica
?
x * 32000-35000
Mucor bacilliformis
?
x * 33000
Mucor circinelloides
?
x * 35000
Mucor renninus
?
x * 41000
Penicillium duponti
?
x * 20000-43000
Rhizomucor miehei
?
x * 38500, SDS-PAGE
Rhizomucor pusillus
?
x * 34000
Rhizopus oryzae
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
45
-
-
Mucor bacilliformis
50
-
-
Amylomyces rouxii
55
-
-
Aspergillus oryzae
55
-
-
Penicillium duponti
55
-
-
Rhizomucor pusillus
58
62
-
Rhizomucor miehei
60
-
-
Rhizopus oryzae
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.5
-
-
Penicillium duponti
3
3.5
-
Mucor bacilliformis
3
3.5
-
Mucor circinelloides
3
3.5
-
Mucor hiemalis
3
-
-
Mucor racemosus f. racemosus
3.2
-
-
Aspergillus oryzae
3.5
-
-
Mucor renninus
4
-
-
Amylomyces rouxii
4.5
-
-
Cryphonectria parasitica
5.5
-
-
Rhizopus oryzae
5.6
-
-
Rhizomucor miehei
5.6
-
-
Rhizomucor pusillus
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Penicillium duponti
isoelectric focusing
-
3.9
Rhizomucor pusillus
isoelectric focusing
-
3.9
Rhizomucor miehei
isoelectric focusing
-
4.1
Mucor circinelloides
isoelectric focusing
-
4.2
Mucor renninus
isoelectric focusing
-
5.1
Mucor bacilliformis
isoelectric focusing
-
5.2
Cryphonectria parasitica
isoelectric focusing
-
5.5
Other publictions for EC 3.4.23.23
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743030
da Silva
Evaluation of the catalytic s ...
Rhizomucor miehei
J. Ind. Microbiol. Biotechnol.
43
1059-1069
2016
-
-
-
-
-
-
4
7
-
5
-
-
-
1
-
-
-
-
-
-
1
-
8
1
1
2
1
6
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
4
-
7
-
5
-
-
-
-
-
-
-
-
1
-
8
1
1
2
1
6
1
1
1
-
-
-
-
-
7
7
717133
Yegin
Aspartic proteinases from Muco ...
Amylomyces rouxii, Aspergillus oryzae, Cryphonectria parasitica, Mucor bacilliformis, Mucor circinelloides, Mucor hiemalis, Mucor racemosus f. racemosus, Mucor renninus, Penicillium duponti, Rhizomucor miehei, Rhizomucor pusillus, Rhizopus oryzae
Appl. Microbiol. Biotechnol.
89
949-960
2011
-
-
-
-
-
-
12
-
-
-
7
-
-
12
-
-
-
-
-
-
-
-
48
10
7
-
-
-
12
-
-
-
-
7
-
-
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Structural and functional dete ...
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Ledward
Structural and functional dete ...
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Rickert
Structural and functional dete ...
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Rickert
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1
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30566
Morihara
Comparative specificity of mic ...
Rhizomucor miehei
Arch. Biochem. Biophys.
157
561-572
1973
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3
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30641
Rickert
Acid proteases from species of ...
Rhizomucor miehei
Can. J. Biochem.
51
1638-1646
1973
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1
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1
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1
1
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1
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1
1
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30663
Oka
-
Specificity of a Renninlike en ...
Rhizomucor pusillus
Agric. Biol. Chem.
37
1177-1184
1973
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2
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30664
Oka
Comparative specificity of mic ...
Rhizomucor miehei
Arch. Biochem. Biophys.
156
552-559
1973
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1
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3
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3
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30665
Oka
Comparative specificity of mic ...
Rhizomucor miehei
Arch. Biochem. Biophys.
156
543-551
1973
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1
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2
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30666
Sanner
Kinetic studies on the aggrega ...
Rhizomucor pusillus
Biochim. Biophys. Acta
303
68-76
1973
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1
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1
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1
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1
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1
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2
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30667
Sternberg
Bond specificity, active site ...
Rhizomucor miehei
Biochim. Biophys. Acta
285
383-392
1972
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2
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1
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9
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2
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9
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30669
Rickert
Structural and functional dete ...
Rhizomucor miehei
Biochim. Biophys. Acta
271
93-101
1972
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1
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1
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1
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30670
Takahshi
Inactivation of acid proteases ...
Rhizomucor pusillus
J. Biochem.
71
161-164
1972
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1
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1
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1
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30671
Yu
-
Milk-clotting enzyme from micr ...
Rhizomucor pusillus
Agric. Biol. Chem.
35
1398-1401
1971
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1
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1
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1
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30672
Yu
-
Milk-clotting enzyme from micr ...
Rhizomucor pusillus
Agric. Biol. Chem.
35
1194-1199
1971
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1
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1
1
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1
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1
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30674
Voynick
The comparative specificity of ...
Rhizomucor miehei
Proc. Natl. Acad. Sci. USA
68
257-259
1971
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1
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1
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1
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1
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1
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1
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1
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30642
Ottesen
The isolation and partial char ...
Rhizomucor miehei
C. R. Trav. Lab. Carlsberg
37
301-325
1970
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1
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1
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1
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1
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1
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1
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1
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30668
Arima
-
Milk-clotting enzyme for Mucor ...
Rhizomucor pusillus
Methods Enzymol.
19
446-459
1970
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1
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2
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2
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1
1
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1
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1
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11
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2
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3
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1
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1
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2
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2
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1
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1
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1
-
11
-
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2
-
3
-
1
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30673
Ottesen
-
Acid protease of Mucor miehei ...
Rhizomucor miehei
Methods Enzymol.
19
459-460
1970
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1
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1
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1
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1
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1
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2
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1
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1
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1
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1
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1
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1
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2
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1
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1
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30676
Yu
Milk-clotting enzyme from micr ...
Rhizomucor pusillus
Biochim. Biophys. Acta
171
138-144
1969
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1
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1
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2
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1
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2
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30675
Arima
Milk-clotting enzyme from micr ...
Rhizomucor pusillus
Appl. Microbiol.
16
1727-1733
1968
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1
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4
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3
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1
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1
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1
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4
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1
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1
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30677
Yu
-
Release of sialic acid from ka ...
Rhizomucor pusillus
Agric. Biol. Chem.
32
1482-1483
1968
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1
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1
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1
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1
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-
1
-
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30678
Yu
-
The active site of Mucor-renni ...
Rhizomucor pusillus
Agric. Biol. Chem.
32
1048-1050
1968
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1
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1
1
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1
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1
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1
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1
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30679
Somkuti
Purification and properties of ...
Rhizomucor pusillus
J. Bacteriol.
95
1407-1414
1968
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7
1
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1
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1
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1
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2
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1
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2
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1
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7
-
1
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1
-
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1
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2
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1
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2
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1
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