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Literature summary for 3.4.23.17 extracted from
- Chromaffin granule aspartic proteinase processes recombinant proopiomelanocortin (POMC) (1995), Biochem. Biophys. Res. Commun., 215, 937-944.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pepstatin A | - |
Bos taurus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chromaffin granule | - |
Bos taurus | 42583 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
bovine | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal medulla | - |
Bos taurus | - |
| hypophysis | neural | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Pro-opiomelanocortin + H2O | - |
Bos taurus | Adrenocorticotropin + beta-lipotropin | a 27000 and 22000 Da band detected by anti-N-proopiomelanocortin immunoblots and to 26000 Da, 22000 Da and 14000 DA bands that are immunoreactive with anti-beta-lipotropin | ? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 70000, bovine | Bos taurus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
acidic pH optimum | Bos taurus |
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Release 2023.1 (January 2023)
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