Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Diazoacetylnorleucine methyl ester | - |
Bos taurus | |
leupeptin | - |
Bos taurus | |
pepstatin A | - |
Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0019 | - |
beta-Lipotropin | human substrate, cleavage at Lys37-Lys38 | Bos taurus | |
0.0025 | - |
beta-Lipotropin | human substrate, cleavage at Lys57-Arg58 | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypophysis | intermediate | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Human beta-lipotropin + H2O | cleavage at two of the three pairs of basic residues of human beta-lipotropin, at Lys37-Lys38 and Lys57-Arg58, but not at Lys86-Lys87, the cleavage at Lys57-Arg58 occurs primarily between these basic residues | Bos taurus | More | at enzyme concentration of 20 ng/0.1 ml: gamma-lipotropin + a beta-melanotropin linked to beta-endorphin intermediate + beta-endorpin, at enzyme concentration of 40 ng/0.1 ml: complete cleavage to yield beta-endorphin + beta-melanotrophin | ? | |
Pro-opiomelanocortin + H2O | - |
Bos taurus | Adrenocorticotropin + beta-lipotropin | - |
? |