Literature summary for 3.4.23.16 extracted from

Vathipadiekal, V.; Umasankar, P.K.; Patole, M.S.; Rao, M.
Molecular cloning, over expression, and activity studies of a peptidic HIV-1 protease inhibitor: designed synthetic gene to functional recombinant peptide (2010), Peptides, 31, 16-21.

Search for more literature for 3.4.23.16

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli	Human immunodeficiency virus 1

Inhibitors

Inhibitors	Comment	Organism	Structure
ATBI	aspartic protease inhibitor: Ala-Gly-Lys-Lys-Asp-Asp-Asp-Asp-Pro-Pro-Glu, from Bacillus sp.	Human immunodeficiency virus 1

Organism

Organism	UniProt	Comment	Textmining
Human immunodeficiency virus 1	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Lys-Ala-Arg-Val-Nle-(p-nitro-Phe)-Glu-Ala-Nle-amide + H2O	-	Human immunodeficiency virus 1	Lys-Ala-Arg-Val-Nle + (p-nitro-Phe)-Glu-Ala-Nle-amide	-	?

Synonyms

Synonyms	Comment	Organism
HIV-1 protease	-	Human immunodeficiency virus 1

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000017	-	ATBI	natural ATBI	Human immunodeficiency virus 1
0.07	-	ATBI	recombinant ATBI	Human immunodeficiency virus 1

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0000178	-	natural ATBI	Human immunodeficiency virus 1	ATBI
0.072	-	recombinant ATBI	Human immunodeficiency virus 1	ATBI

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)