Protein Variants | Comment | Organism |
---|---|---|
additional information | protease lacking the terminal residues 1-4 and 96-99 exhibits a stable monomer fold | Human immunodeficiency virus 1 |
T26A | mutation increases the stability of the monomer fold, mutant still exhibits a high Kd value of more than 0.5 mM | Human immunodeficiency virus 1 |
Organic Solvent | Comment | Organism |
---|---|---|
urea | the urea-induced unfolding transition of the protease monomer even lacking the interfacial terminal 4 residues (PR5-95) is similar to that of the pseudo wild-type active or the inactive (PRD25N) dimers with a transition mid-point of about 1.9 M urea | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Lys-Ala-Arg-Val-Nle-(4-nitrophenylalanine)-Glu-Ala-Nle-NH2 + H2O | - |
Human immunodeficiency virus 1 | Lys-Ala-Arg-Val-Nle + (4-nitrophenylalanine)-Glu-Ala-Nle-NH2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HIV-1 protease | - |
Human immunodeficiency virus 1 |