Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.23.16 extracted from

  • Shuman, C.F.; Haemaelaeinen, M.D.; Danielson, U.H.
    Kinetic and thermodynamic characterization of HIV-1 protease inhibitors (2004), J. Mol. Recognit., 17, 106-119.
    View publication on PubMed

Application

Application Comment Organism
pharmacology the enzyme is a target for specific inhibitor development Human immunodeficiency virus 1

Inhibitors

Inhibitors Comment Organism Structure
amprenavir
-
Human immunodeficiency virus 1
indinavir
-
Human immunodeficiency virus 1
lopinavir
-
Human immunodeficiency virus 1
ritonavir
-
Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
i.e. HIV-1
-

Synonyms

Synonyms Comment Organism
HIV-1 protease
-
Human immunodeficiency virus 1

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
additional information kinetic and thermodynamic characterization of HIV-1 protease inhibitors using a biosensor-based method, overview Human immunodeficiency virus 1