Literature summary for 3.4.23.16 extracted from

Surleraux, D.L.; de Kock, H.A.; Verschueren, W.G.; Pille, G.M.; Maes, L.J.; Peeters, A.; Vendeville, S.; De Meyer, S.; Azijn, H.; Pauwels, R.; de Bethune, M.P.; King, N.M.; Prabu-Jeyabalan, M.; Schiffer, C.A.; Wigerinck, P.B.
Design of HIV-1 protease inhibitors active on multidrug-resistant virus (2005), J. Med. Chem., 48, 1965-1973.

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Application

Application	Comment	Organism
drug development	the enzyme is a target for drug development	Human immunodeficiency virus 1
pharmacology	the enzyme is a target for drug development active on multidrug-resistant virus	Human immunodeficiency virus 1

Inhibitors

Inhibitors	Comment	Organism	Structure
amprenavir	-	Human immunodeficiency virus 1
atazanavir	-	Human immunodeficiency virus 1
indinavir	-	Human immunodeficiency virus 1
lopinavir	-	Human immunodeficiency virus 1
additional information	design of enzyme inhibitors active on multidrug-resistant virus, overview	Human immunodeficiency virus 1
nelfinavir	-	Human immunodeficiency virus 1
ritonavir	-	Human immunodeficiency virus 1
saquinavir	-	Human immunodeficiency virus 1
tipranavir	-	Human immunodeficiency virus 1

Organism

Organism	UniProt	Comment	Textmining
Human immunodeficiency virus 1	-	i.e. HIV-1	-

Synonyms

Synonyms	Comment	Organism
HIV-1 protease	-	Human immunodeficiency virus 1

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Release 2023.1 (January 2023)