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Literature summary for 3.4.23.15 extracted from
- Direct renin inhibition: an update (2009), Curr. Hypertens. Rep., 11, 456-462.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| aliskiren | orally effective direct renin inhibitor, aliskiren inhibits the renin-angiotensin-aldosterone system by blocking the enzymatic activity of renin | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensinogen + H2O | Homo sapiens | - |
angiotensin I + angiotensinogen propeptide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensinogen + H2O | - |
Homo sapiens | angiotensin I + angiotensinogen propeptide | - |
? | |
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Release 2023.1 (January 2023)
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