Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania amazonensis | - |
- |
- |
Leishmania amazonensis MHOM/BR/77 / LTB0016 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
CPB | - |
Leishmania amazonensis |
cysteine-proteinase B | - |
Leishmania amazonensis |
General Information | Comment | Organism |
---|---|---|
physiological function | CPB is an important virulence factor, it inhibits lymphocytes Th1 and/or promotes Th2 responses either through proteolytic activity or through epitopes derived from its COOH-terminal extension. Some peptides from the CPB COOH-terminal extension influence host immune responses in the murine infection, thus helping Leishmania survival | Leishmania amazonensis |