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Literature summary for 3.4.22.B30 extracted from

  • Arrington, D.; Van Vleet, T.; Schnellmann, R.
    Calpain 10: a mitochondrial calpain and its role in calcium-induced mitochondrial dysfunction (2006), Am. J. Physiol. Cell Physiol., 291, C1159-1171.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Ca2+
-
Oryctolagus cuniculus
Ca2+
-
Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
-
Oryctolagus cuniculus
-
Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
calpeptin
-
Oryctolagus cuniculus
calpeptin
-
Rattus norvegicus
E-64
-
Oryctolagus cuniculus
E-64
-
Rattus norvegicus
additional information the enzyme is not inhibited by PD150606 Oryctolagus cuniculus
additional information the enzyme is not inhibited by PD150606 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion mitochondrial outer membrane, intermembrane space, inner membrane, matrix Oryctolagus cuniculus 5739
-
mitochondrion mitochondrial outer membrane, intermembrane space, inner membrane, matrix Rattus norvegicus 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activates calpain 10 Oryctolagus cuniculus
Ca2+ activates calpain 10 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
x * 75000, SDS-PAGE Oryctolagus cuniculus
75000
-
x * 75000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
New Zealand white rabbit
-
Rattus norvegicus Q9ES66
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Oryctolagus cuniculus
-
kidney
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
FITC-casein + H2O in the presence of CaCl2 Oryctolagus cuniculus FITC + casein
-
?
FITC-casein + H2O in the presence of CaCl2 Rattus norvegicus FITC + casein
-
?
additional information DAP13 (13 kDa differentiation-associated protein) is not hydrolyzed by calpain 10 in the presence of CaCl2 Oryctolagus cuniculus ?
-
?
additional information DAP13 (13 kDa differentiation-associated protein) is not hydrolyzed by calpain 10 in the presence of CaCl2 Rattus norvegicus ?
-
?
ND6 subunit of complex I + H2O in the presence of CaCl2 Oryctolagus cuniculus ?
-
?
ND6 subunit of complex I + H2O in the presence of CaCl2 Rattus norvegicus ?
-
?
NDUFV2 + H2O in the presence of CaCl2 Oryctolagus cuniculus ?
-
?
NDUFV2 + H2O in the presence of CaCl2 Rattus norvegicus ?
-
?
SLLVYAMC + H2O in the presence of CaCl2 Oryctolagus cuniculus SLLVY + AMC
-
?
SLLVYAMC + H2O in the presence of CaCl2 Rattus norvegicus SLLVY + AMC
-
?

Subunits

Subunits Comment Organism
? x * 75000, SDS-PAGE Oryctolagus cuniculus
? x * 75000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
calpain 10
-
Oryctolagus cuniculus
calpain 10
-
Rattus norvegicus