Literature summary for 3.4.22.B25 extracted from

Waghray, A.; Wang, D.S.; McKinsey, D.; Hayes, R.L.; Wang, K.K.
Molecular cloning and characterization of rat and human calpain-5 (2004), Biochem. Biophys. Res. Commun., 324, 46-51.

Search for more literature for 3.4.22.B25

Cloned(Commentary)

Cloned (Comment)	Organism
-	Rattus norvegicus
-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
MDL-28170	blocks calpain-5 processing	Homo sapiens
N-ethylmaleimide	blocks calpain-5 processing	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	calpain-5 is processed or autolyzed in the presence of Ca2+	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
76000	-	calculated from amino acid sequence	Rattus norvegicus
76000	-	1 * 76000, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15484	-	-
Rattus norvegicus	Q8R4C0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	strong expression	Rattus norvegicus	-
brain	strong expression	Homo sapiens	-
cerebellum	strong expression	Homo sapiens	-
colon	strong expression	Homo sapiens	-
frontal lobe	strong expression	Homo sapiens	-
heart	weak expression	Rattus norvegicus	-
hypothalamus	strong expression	Homo sapiens	-
kidney	strong expression	Rattus norvegicus	-
lung	strong expression	Rattus norvegicus	-
medulla oblongata	strong expression	Homo sapiens	-
SH-SY5Y cell	-	Homo sapiens	-
testis	strong expression	Homo sapiens	-
thalamus	strong expression	Homo sapiens	-

Subunits

Subunits	Comment	Organism
monomer	1 * 76000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
calpain-5	-	Rattus norvegicus
calpain-5	-	Homo sapiens

pI Value

Organism	Comment	pI Value Maximum	pI Value
Rattus norvegicus	calculated from amino acid sequence	-	7.6

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Release 2023.1 (January 2023)