Application | Comment | Organism |
---|---|---|
medicine | Bacillus anthracis SrtA anchors surface proteins bearing LPXTG motif sorting signals to the cell wall envelope of vegetative bacilli, srtA gene of Bacillus anthracis is not required for the development of acute anthrax disease in A/J mice | Bacillus anthracis |
Cloned (Comment) | Organism |
---|---|
cloned into the plasmid vector pQE30 | Bacillus anthracis |
Protein Variants | Comment | Organism |
---|---|---|
additional information | srtA mutants AHG263 (srtA gene deleted by allelic replacement with ermC marker) and AHG188 | Bacillus anthracis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2-(trimethylammonium)ethyl)methanethiosulfonate | inhibition at 5 mM, inhibition is relieved by supplementing the reaction with 10 mM dithiothreitol | Bacillus anthracis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23000 | - |
SDS-PAGE, immune-reactive species | Bacillus anthracis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus anthracis | - |
parent strain Sterne 34F2 | - |
Purification (Comment) | Organism |
---|---|
by Ni-NTA affinity chromatography | Bacillus anthracis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-aminobenzoyl-LPATG-diaminopropionic acid + H2O | efficient cleavage | Bacillus anthracis | 2-aminobenzoyl-LPAT + G-diaminopropionic acid | - |
? | |
2-aminobenzoyl-LPNTA-diaminopropionic acid + H2O | small amount of cleavage | Bacillus anthracis | 2-aminobenzoyl-LPNT + A-diaminopropionic acid | - |
? | |
Abz-LPETG-Dap(Dnp) + H2O | cleavage between the threonine and the glycine residues, efficient cleavage | Bacillus anthracis | Abz-LPET + G-Dap(Dnp) | - |
? | |
additional information | no cleavage of 2-aminobenzoyl-NPKTG-diaminopropionic acid and 2-aminobenzoyl-LGATG-diaminopropionic acid | Bacillus anthracis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SrtA | - |
Bacillus anthracis |