Literature summary for 3.4.22.68 extracted from

Xu, Y.; Li, J.; Zuo, Y.; Deng, J.
Wang, L.S.; Chen, G.Q.: SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors (2011), Cancer Lett., 309, 78-84.

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Organism

Organism	UniProt	Comment	Textmining

General Information

General Information	Comment	Organism
evolution	SENP1 is a member of SENP family	Homo sapiens
malfunction	slencing of SENP1 inhibits growth and colony formation of DLD-1 cells, results in G1-phase arrest, and upregulates the expression of some CDK inhibitors, overview	Homo sapiens
physiological function	SENP1 is essential for cell growth in the colon cancer cell line. SENP1 might play a role in cell cycle regulation of colon cancer cells	Homo sapiens

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Release 2023.1 (January 2023)