Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.65 extracted from

  • Kato, T.; Takai, T.; Mitsuishi, K.; Okumura, K.; Ogawa, H.
    Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases (2005), J. Allergy Clin. Immunol., 116, 169-176.
    View publication on PubMed
Search for more literature for 3.4.22.65

Application

Application Comment Organism
medicine cystatin A produced by keratinocytes is the dominant biochemical skin barrier against mite cysteine proteases Dermatophagoides farinae

Inhibitors

Inhibitors Comment Organism Structure
cystatin A sweat inhibitor, upregulation of IL-8 secretion by stimulation of human keratinocytes by Der f 1 is blocked Dermatophagoides farinae

Organism

Organism UniProt Comment Textmining
Dermatophagoides farinae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Azocoll + H2O collagen substrate Dermatophagoides farinae ?
-
 ?
butyloxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
-
 Dermatophagoides farinae ?
-
 ?
human CD23 + H2O human low-affinity IgE receptor Dermatophagoides farinae ?
-
 ?
human CD25 + H2O alpha subunit of the human IL-2 receptor Dermatophagoides farinae ?
-
 ?

Synonyms

Synonyms Comment Organism
Der f 1
-
 Dermatophagoides farinae