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Literature summary for 3.4.22.65 extracted from

  • Wong, C.K.; Li, M.L.; Wang, C.B.; Ip, W.K.; Tian, Y.P.; Lam, C.W.
    House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells (2006), Int. Immunol., 18, 1327-1335.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information Der p 1 induce the release of IL-1beta, IL-6, IL-10, tumor necrosis factor-alpha and granulocyte macrophage colony-stimulating factor from eosinophils, surface expression of CD18 and ICAM-1, can activate NK-KB, AP-1 activity and p38 MAPK in BEAS-2B cells and eosinophils alone and in co-culture Dermatophagoides pteronyssinus

Application

Application Comment Organism
medicine induces biological responses in a human airway-derived epithelial cell line Dermatophagoides pteronyssinus

Organism

Organism UniProt Comment Textmining
Dermatophagoides pteronyssinus
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
Der p 1
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Dermatophagoides pteronyssinus