Literature summary for 3.4.22.63 extracted from

Kim, M.S.; Oh, J.E.; Min, C.K.; Lee, S.; Chung, N.G.; Yoo, N.J.; Lee, S.H.
Mutational analysis of CASP10 gene in acute leukaemias and multiple myelomas (2009), Pathology, 41, 484-487.

Search for more literature for 3.4.22.63

Protein Variants

Protein Variants	Comment	Organism
L285P	the mutation may contribute to the pathogenesis of factions of T-acute lymphoblastic leukemia and multiple myeloma	Homo sapiens
R21C	the mutation may contribute to the pathogenesis of factions of T-acute lymphoblastic leukemia and multiple myeloma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leukemia cell	-	Homo sapiens	-
multiple myeloma cell	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	caspase-10 activation is important in the initiation phase of apoptosis	Homo sapiens

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Release 2023.1 (January 2023)