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Literature summary for 3.4.22.62 extracted from

  • Blanch, R.J.; Ahmed, Z.; Thompson, A.R.; Akpan, N.; Snead, D.R.; Berry, M.; Troy, C.M.; Scott, R.A.; Logan, A.
    Caspase-9 mediates photoreceptor death after blunt ocular trauma (2014), Invest. Ophthalmol. Vis. Sci., 55, 6350-6357.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.62

Inhibitors

Inhibitors Comment Organism Structure
Pen-1-XBIR3 caspase-9 is inhibited by unilateral intravitreal injection of highly specific X-linked inhibitor of apoptosis (IAP) baculoviral IAP repeat 3 (XBIR3) domain linked to the cell transduction peptide penetratin 1 (Pen-1) after ballistic injury Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
photoreceptor outer segment
-
 Rattus norvegicus 1750
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
eye
-
 Rattus norvegicus
-
retina Immunohistochemical locaization of enzyme in outer retina layers, overview Rattus norvegicus
-

General Information

General Information Comment Organism
malfunction caspase-9 inhibition induces functional neuroprotection Rattus norvegicus
physiological function caspase-9 mediates traumatic photoreceptor death, contribution of caspase-9 to photoreceptor death in commotio retinae, overview Rattus norvegicus