Literature summary for 3.4.22.62 extracted from

Samraj, A.K.; Sohn, D.; Schulze-Osthoff, K.; Schmitz, I.
Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization (2007), Mol. Biol. Cell, 18, 84-93.

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining
JURKAT cell	caspase-9 is indispensable for drug-induced apoptosis in cancer cells. Caspase-9 is not only required for loss of mitochondrial membrane potential but also for caspase-2 activation	Homo sapiens	-

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Release 2023.1 (January 2023)