Literature summary for 3.4.22.62 extracted from

Papandile, A.; Tyas, D.; OMalley, D.M.; Warner, C.M.
Analysis of caspase-3, caspase-8 and caspase-9 enzymatic activities in mouse oocytes and zygotes (2004), Zygote, 12, 57-64.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	detection of both caspase-8 and caspase-9 activity in oocytes shows that unfertilized oocytes have the machinery to undergo apoptosis by using either the extrinsic (caspase-8 dependent) or intrinsic (caspase-9 dependent) pathways	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
oocyte	no difference in caspase-9 activity in oocytes compared with zygotes. Cultures of oocytes in staurosporine increases the activity of caspase-9	Mus musculus	-
zygote	no difference in caspase-9 activity in oocytes compared with zygotes	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	detection of both caspase-8 and caspase-9 activity in oocytes shows that unfertilized oocytes have the machinery to undergo apoptosis by using either the extrinsic (caspase-8 dependent) or intrinsic (caspase-9 dependent) pathways	Mus musculus	?	-	?

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Release 2023.1 (January 2023)