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Literature summary for 3.4.22.62 extracted from
- p53, Apaf-1, caspase-3, and -9 are dispensable for Cdk5 activation during cell death (2006), Cell Death Differ., 13, 141-150.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | caspase-9 is dispensable for activation of cyclin-dependent kinase 5 during cell death | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| C8 cell | mouse embryonic fibroblast cell oncogenically transformed with both E1A and ras, and containing wild-type p53 | Mus musculus | - |
| C9 cell | mouse embryonic fibroblast cell oncogenically transformed with both E1A and ras, and containing p53-/- | Mus musculus | - |
| embryonic fibroblast cell line | mouse embryonic fibroblast cell oncogenically transformed with both E1A and ras, and containing p53-/- | Mus musculus | - |
| embryonic fibroblast cell line | mouse embryonic fibroblast cell oncogenically transformed with both E1A and ras, and containing wild-type p53 | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | caspase-9 is dispensable for activation of cyclin-dependent kinase 5 during cell death | Mus musculus | ? | - |
? | |
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