Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | tumor necrosis factor alpha stimulation results in a caspase-8-dependent Her-2 cleavage in MCF-7 breast adenocarcinoma cells defective for nuclear factor kappaB activation | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
HER-2 + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast adenocarcinoma cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
HER-2 + H2O | - |
Homo sapiens | ? | - |
? | |
IEPD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | IEPD + 7-amino-4-methylcoumarin | - |
? |