Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macrophage | - |
Homo sapiens | - |
U-937 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
FLICE | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | inactivation of protein-associated splicing factor by siRNA significantly decreases the level of caspase-8 in macrophages, significant suppression of caspase-8 activation is observed in both macrophages infected with wild type Mycobacterium tuberculosis H37Rv and with the complemented 31G12 strain containing the pLD31G12-3 construct | down |
Homo sapiens | recombinant tumor necrosis actor-alpha-treated and Mycobacterium tuberculosis 31G12-infected macrophages show caspase-8 activation | up |