Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.61 extracted from

  • Goel, A.; Prasad, A.K.; Parmar, V.S.; Ghosh, B.; Saini, N.
    Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung adenocarcinoma cell line: role of NF-kappaB, Akt, ROS and MAP kinase pathway (2009), Chem. Biol. Interact., 179, 363-374.
    View publication on PubMed
Search for more literature for 3.4.22.61

Activating Compound

Activating Compound Comment Organism Structure
additional information the antioxidant 7,8-diacetoxy-4-methylcoumarin, DAMC, and its thiocoumarin derivative 7,8-diacetoxy-4-methylthiocoumarin, DAMTC, induce apoptosis by activating caspase-9 and caspase-3 without affecting the activity of caspase-8 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
lung adenocarcinoma cell
-
 Homo sapiens
-
non-small cell lung cancer cell
-
 Homo sapiens
-