Application | Comment | Organism |
---|---|---|
drug development | gastric cancer might be a good target of TRAIL therapy because the majority of tumor cells have intact caspase-8 expression. The anticancer efficacy may be predicted by the degree of caspase-8 activation after TRAIL treatment | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
18000 | - |
fragment of caspase-8 resulting from cleavage, SDS-PAGE | Homo sapiens |
43000 | - |
fragment of caspase-8 resulting from cleavage, SDS-PAGE | Homo sapiens |
57000 | - |
monomer, full-length unactivated form, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q14790 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gastric cell line | OCUM-2M, OCUM-1, OCUM-8, OCUM-9, NUGC3, NIGC4, MKN45, MKN74, FU97, MKN7 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
caspase-8 | - |
Homo sapiens |