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Literature summary for 3.4.22.61 extracted from

  • Dohrman, A.; Kataoka, T.; Cuenin, S.; Russell, J.Q.; Tschopp, J.; Budd, R.C.
    Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation (2005), J. Immunol., 174, 5270-5278.
    View publication on PubMed
Search for more literature for 3.4.22.61

Activating Compound

Activating Compound Comment Organism Structure
cellular FLIP long form
-
 Mus musculus

Application

Application Comment Organism
medicine caspase-8 is required for T cell activation Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
QVD-OPh
-
 Mus musculus
Z-Val-Ala-Asp(OCH3)-fluoromethylketone
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus O89110
-
-

Source Tissue

Source Tissue Comment Organism Textmining
T-lymphocyte CD8+ T cell Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cellular FLIP long form + H2O
-
 Mus musculus ?
-
 ?
DEVD-rhodamine + H2O
-
 Mus musculus rhodamine + DEVD
-
 ?

Synonyms

Synonyms Comment Organism
caspase-8
-
 Mus musculus