Activating Compound | Comment | Organism | Structure |
---|---|---|---|
CD95 | FLICE is the first in a cascade of ICE-like proteases activated by CD95. This activation requires a functional CD95 disc | Mus musculus | |
CD95 | FLICE is the first in a cascade of ICE-like proteases activated by CD95. This activation requires a functional CD95 disc | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | FLICE is the first in a cascade of ICE-like proteases activated by CD95. Active FLICE is released into the cytosol, where it can activate a cascade of ICE-like proteases | ? | - |
? | |
additional information | Homo sapiens | FLICE is the first in a cascade of ICE-like proteases activated by CD95. Active FLICE is released into the cytosol, where it can activate a cascade of ICE-like proteases | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
BL-60 cell | - |
Homo sapiens | - |
H9 cell | - |
Homo sapiens | - |
HUT78 cell | - |
Homo sapiens | - |
L-929 cell | fibroblastoid cell line | Mus musculus | - |
SKW6.4 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | FLICE is the first in a cascade of ICE-like proteases activated by CD95. Active FLICE is released into the cytosol, where it can activate a cascade of ICE-like proteases | Mus musculus | ? | - |
? | |
additional information | FLICE is the first in a cascade of ICE-like proteases activated by CD95. Active FLICE is released into the cytosol, where it can activate a cascade of ICE-like proteases | Homo sapiens | ? | - |
? |