Literature summary for 3.4.22.60 extracted from

Siniscalco, D.; Giordano, C.; Fuccio, C.; Luongo, L.; Ferraraccio, F.; Rossi, F.; de Novellis, V.; Roth, K.A.; Maione, S.
Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats (2008), Pharmacol. Res., 57, 223-233.

Search for more literature for 3.4.22.60

Cloned(Commentary)

Cloned (Comment)	Organism
RT-PCR enzyme expression analysis in the central nervous system of neuropathic rats	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	non-selective 1-aminoindan-1,5-dicarboxylic acid and selective (3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl) methanone lead to reduced enzyme expression in in the dorsal horn spinal cord by 3 days post-chronic constrictive injury, overview	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male Wistar rats, neuropathic rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
sciatic nerve	increased expression of caspase-7 mRNA in the dorsal horn spinal cord by 3 days post-chronic constrictive injury	Rattus norvegicus	-
spinal cord	-	Rattus norvegicus	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)