Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | Escherichia coli lipopolysaccharides induce the enzyme in splenocytes | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | contsruction of caspase-7-deficient mice, that show protection from endotoxin-induced lymphocyte apoptosis and improved survival, phenotype, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | the apoptotic executioner caspase-7 is activated in the splenocytes of lipopolysaccharide-injected mice, suggesting a role for caspase-7 in lymphocyte apoptosis. Caspase-7 deficiency and caspase inhibition protect from endotoxin-induced lymphocyte apoptosis and improve survival | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | - |
Mus musculus | - |
splenocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the apoptotic executioner caspase-7 is activated in the splenocytes of lipopolysaccharide-injected mice, suggesting a role for caspase-7 in lymphocyte apoptosis. Caspase-7 deficiency and caspase inhibition protect from endotoxin-induced lymphocyte apoptosis and improve survival | Mus musculus | ? | - |
? |