Application | Comment | Organism |
---|---|---|
medicine | strong correlation between caspase-7 activity, normal brain development, and apoptotic DNA fragmenation in Casp3-/-mice | Homo sapiens |
medicine | strong correlation between caspase-7 activity, normal brain development, and apoptotic DNA fragmenation in Casp3-/-mice, caspase-7 is a caspase-3 surrogate in Casp3-/-mice | Mus musculus |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
cloned into the NcoI site of the pET11d vector and expression in Escherichia coli BL21codon+ | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
B6 and 129 strain, adults and embryos | - |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
stomach | - |
Mus musculus | - |
telencephalon | precursor neurons | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ac-DEVD-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | Ac-DEVD + 7-amino-4-methylcoumarin | - |
? | |
inhibitor of caspase-actived DNase + H2O | human caspase-7 is less efficient than caspase-3 at cleaving | Homo sapiens | ? | - |
? | |
inhibitor of caspase-actived DNase + H2O | mouse caspase-7 and caspase-3 are equally efficient at cleaving | Mus musculus | ? | - |
? |