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Literature summary for 3.4.22.60 extracted from

  • Lippke, J.A.; Gu, Y.; Sarnecki, C.; Caron, P.R.; Su, M.S.S.
    Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32 (1996), J. Biol. Chem., 271, 1825-1828.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in COS cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P55210
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification
-
Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no cleavage of interleukin 1beta precursor Homo sapiens ?
-
?
poly(ADP-ribose) polymerase + H2O
-
Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
More it is proposed that the 22000 Da peptide and the 12000 Da peptide are two subunits of the enzyme Homo sapiens