Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
x * 32000, pro-enzyme, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
huntingtin + H2O | Mus musculus | the enzyme cleaves at Asp-586 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain cortex | - |
Mus musculus | - |
striatum | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
huntingtin + H2O | the enzyme cleaves at Asp-586 | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 32000, pro-enzyme, SDS-PAGE | Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme plays a role in clearance pathways for the huntingtin protein whose proteolysis is a critical pathological event in Huntington's diesease | Mus musculus |