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Literature summary for 3.4.22.59 extracted from
- The structure of procaspase 6 is similar to that of active mature caspase 6 (2002), Biochem. J., 364, 629-634.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D316A | to prevent autocatalytic processing of the specific site of procaspase 6, Asp316 of rCaspase 6 is replaced with Ala | Homo sapiens |
| W175F | reduced autocatalytic processing activity | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| purified to homogeneity | Homo sapiens |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | procaspase 6, SDS-PAGE, chemical cross-linking and gel filtration, nearly identical CD spectra of rCaspase 6 and D316A caspase 6, indicating that overal structures of both precursor and mature forms of caspase 6 should be almost indistinguishable | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| caspase 6 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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