Literature summary for 3.4.22.58 extracted from

Faucheu, C.; Blanchet, A.M.; Collard-Dutilleul, V.; Lalanne, J.L.; Diu-Hercend, A.
Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme (1996), Eur. J. Biochem., 236, 207-213.

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Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in COS cells	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	the enzyme is able to induce apoptosis when overexpressed in COS cells	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P51878	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme fails to process the interleukin-1beta precursor, activity is dependent on the presence of a cysteine residue at position 245	Homo sapiens	?	-	?
additional information	the enzyme is able to induce apoptosis when overexpressed in COS cells	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)