Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.58 extracted from

  • Garcia-Calvo, M.; Peterson, E.P.; Leiting, B.; Ruel, R.; Nicholson, D.W.; Thornberry, N.A.
    Inhibition of human caspases by peptide-based and macromolecular inhibitors (1998), J. Biol. Chem., 273, 32608-32613.
    View publication on PubMed
Search for more literature for 3.4.22.58

Inhibitors

Inhibitors Comment Organism Structure
acetyl-AEVD-aldehyde
-
 Homo sapiens
acetyl-DEVD-aldehyde
-
 Homo sapiens
acetyl-IETD-aldehyde
-
 Homo sapiens
acetyl-WEHD-aldehyde
-
 Homo sapiens
acetyl-YVAD-aldehyde
-
 Homo sapiens
benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone t1/2 at 0.001 mM Homo sapiens
cowpox serpin CrmA
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
 additional information the Ki-value for cowpox serpin CrmA is below below 0.1 nM Homo sapiens
0.000043
-
 acetyl-WEHD-aldehyde pH 7.5, 25°C Homo sapiens
0.000163
-
 acetyl-YVAD-aldehyde pH 7.5, 25°C Homo sapiens
0.000205
-
 acetyl-IETD-aldehyde pH 7.5, 25°C Homo sapiens
0.000223
-
 acetyl-WEHD-aldehyde pH 7.5, 25°C Homo sapiens
0.000438
-
 acetyl-AEVD-aldehyde pH 7.5, 25°C Homo sapiens