Literature summary for 3.4.22.57 extracted from

Kajiwara, Y.; Akram, A.; Katsel, P.; Haroutunian, V.; Schmeidler, J.; Beecham, G.; Haines, J.L.; Pericak-Vance, M.A.; Buxbaum, J.D.
FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4 (2009), PLoS ONE, 4, e5071.

Search for more literature for 3.4.22.57

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	increase of caspase-4 expression by reduced expression of Teashirt3	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	downregulation of caspase-4 expression in cells expressiong FE65 and Teashirt3	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
no activity in Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
H4 neuroglioma cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
CASP4	-	Homo sapiens
caspase-4	-	Homo sapiens

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Release 2023.1 (January 2023)