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Literature summary for 3.4.22.57 extracted from

  • Koehn, S.; Trueck, M.; Poehlmann, T.G.; Schleussner, E.; Markert, U.R.; Seyfarth, L.
    Assessment of caspase-4 released free AFC by RP-HPLC and fluorescence detection (2008), J. Chromatogr. B, 874, 111-114.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
hepatocyte growth factor
-
Homo sapiens
interleukin 6
-
Homo sapiens
Leukemia inhibitory factor
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
choriocarcinoma cell
-
Homo sapiens
-
JEG-3 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-Leu-Glu-Val-Asp-7-amido-4-trifluoro methylcoumarin + H2O 10 microM, 2 h, 37°C, reaction stopped with HCl Homo sapiens 7-amino-4-trifluoromethylcoumarin + Ac-Leu-Glu-Val-Asp
-
?

Synonyms

Synonyms Comment Organism
caspase-4
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
2 h incubation time Homo sapiens