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Literature summary for 3.4.22.57 extracted from

  • Lakshmanan, U.; Porter, A.G.
    Caspase-4 interacts with TNF receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kappaB-dependent production of IL-8 and CC chemokine ligand 4 (macrophage-inflammatory protein-1) (2007), J. Immunol., 179, 8480-8490.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens P49662 TRAF6-caspase-4 interaction, triggered by LPS, leads to NFkappaB-dependent transcriptional up-regulation and secretion of important cytokines and chemokines in innate immune signaling in human monocytic cells
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