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Literature summary for 3.4.22.57 extracted from

  • Margolin, N.; Raybuck, S.A.; Wilson, K.P.; Chen, W.; Fox, T.; Gu, Y.; Livingston, D.J.
    Substrate and inhibitor specificity of interleukin-1beta-converting enzyme and related caspases (1997), J. Biol. Chem., 272, 7223-7228.
    View publication on PubMed
Search for more literature for 3.4.22.57

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.035
-
 acetyl-YVAD-amido-4-methylcoumarin pH 7.5 Homo sapiens
0.048
-
 succinyl-YVAD-4-nitroanilide pH 7.5 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-YVAD-amido-4-methylcoumarin + H2O
-
 Homo sapiens acetyl-YVAD + amino-4-methylcoumarin
-
 ?
poly(ADP-ribose)polymerase + H2O
-
 Homo sapiens ?
-
 ?
pro-interleukin-1beta + H2O
-
 Homo sapiens additional information
-
 ?
succinyl-YVAD-4-nitroanilide + H2O
-
 Homo sapiens succinyl-YVAD + 4-nitroaniline
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.5
-
 acetyl-YVAD-amido-4-methylcoumarin pH 7.5 Homo sapiens
1.1
-
 succinyl-YVAD-4-nitroanilide pH 7.5 Homo sapiens