Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Z-Asp-2,6-dichlorobenzoyloxymethylketone | a caspase-3-specific inhibitor | Mus musculus | |
Z-VAD-fluoromethylketone | a pan-caspase inhibitor | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow-derived macrophage | - |
Mus musculus | - |
RAW-264 cell | - |
Mus musculus | - |
General Information | Comment | Organism |
---|---|---|
malfunction | caspase-3-specific inhibition augments RANKL-induced osteoclast differentiation in RAW264 cells and mouse bone marrow macrophages | Mus musculus |
physiological function | activation of caspase-3 plays an inhibitory role at the late stage of RANKL-induced osteoclast differentiation | Mus musculus |