Literature summary for 3.4.22.55 extracted from

Thomas, C.N.; Thompson, A.M.; McCance, E.; Berry, M.; Logan, A.; Blanch, R.J.; Ahmed, Z.
Caspase-2 mediates site-specific retinal ganglion cell death after blunt ocular injury (2018), Invest. Ophthalmol. Vis. Sci., 59, 4453-4462 .

Search for more literature for 3.4.22.55

Application

Application	Comment	Organism
medicine	caspase-2 mediates death in a proportion of retinal ganglion cells but not photoreceptors at the site of blunt ocular trauma. Thus, intravitreally delivered siCASP2 is a possible therapeutic for the effective treatment of retinal ganglion cell death to prevent traumatic optic neuropathy	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P55215	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
retina	-	Rattus norvegicus	-

General Information

General Information	Comment	Organism
physiological function	the enzyme mediates site-specific retinal ganglion cell death after blunt ocular injury	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)