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Literature summary for 3.4.22.54 extracted from

  • Ono, Y.; Ojima, K.; Shinkai-Ouchi, F.; Hata, S.; Sorimachi, H.
    An eccentric calpain, CAPN3/p94/calpain-3 (2016), Biochimie, 122, 169-187 .
    View publication on PubMed
Search for more literature for 3.4.22.54

Activating Compound

Activating Compound Comment Organism Structure
calmodulion positive regulator Homo sapiens

General Stability

General Stability Organism
the enzyme undergoes extremely rapid and exhaustive autodegradation Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Ca2+-regulated enzyme Homo sapiens
Na+ activated by Na+ Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P20807
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ALDOA protein + H2O
-
 Homo sapiens ?
-
 ?
ANKRD23/CARP/MARP1 protein + H2O
-
 Homo sapiens ?
-
 ?
beta-oxidation enzyme + H2O
-
 Homo sapiens ?
-
 ?
C/EBPa protein + H2O
-
 Homo sapiens ?
-
 ?
CTBP1 protein + H2O i.e. C-terminal binding protein 1 Homo sapiens ?
-
 ?
ezrin + H2O
-
 Homo sapiens ?
-
 ?
filamin C + H2O
-
 Homo sapiens ?
-
 ?
IkappaB protein + H2O
-
 Homo sapiens ?
-
 ?
MyoD protein + H2O
-
 Homo sapiens ?
-
 ?
spectrin + H2O
-
 Homo sapiens ?
-
 ?
talin + H2O
-
 Homo sapiens ?
-
 ?
vinexin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
CAPN3
-
 Homo sapiens
p94
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction gene mutations causing CAPN3 defects are responsible for limb-girdle muscular dystrophy type 2A (LGMD2A) Homo sapiens